Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

Table 1 Effect of PTX on seizure in mice

Dose of PTX (mg/kg, i.p.)	Number of mice tested	Mice with status epilepticus	Mice surviving status epilepticus	Seizure score ≥ 3	Total mortality
Saline control	6	0	0	0	0
0.25	6	0	0	0	0
0.5	6	0	0	0	0
1	6	2 (33.3%)*	1 (50%)	1 (16.7%)	1 (16.7%)
2	6	5 (83.3%)**	4 (80%)	4 (66.7%)	1 (16.7%)

Effects of PTX on status epilepticus mice. (n = 6 in each group; *P < 0.05 and **P < 0.01 compare the PTX-treated with the saline control group for the corresponding parameters)

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