Laboratory assessment# | All-cause dementia, censored for stroke (n/N = 579/8008)† | Alzheimer’s disease (n/N = 543/8313) | Vascular dementia (n/N = 31/8313) |
---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Granulocytes | 1.13 (0.83–1.56) | 1.03 (0.75–1.42) | 1.99 (0.52–7.55) |
Corrected for platelets and lymphocytes | 1.36 (0.96–1.93) | 1.12 (0.79–1.58) | 1.92 (0.44–8.41) |
Platelets | 1.45 (1.07–1.96)* | 1.59 (1.17–2.17)* | 3.86 (1.02–14.6)* |
Corrected for granulocytes and lymphocytes | 1.47 (1.07–2.02)* | 1.63 (1.18–2.27)* | 3.39 (0.84–13.7) |
Lymphocytes | 0.80 (0.62–1.02) | 0.85 (0.66–1.10) | 0.76 (0.25–2.30) |
Corrected for granulocytes and platelets | 0.76 (0.58–0.98)* | 0.81 (0.62–1.06) | 0.64 (0.20–2.03) |
Granulocyte-to-lymphocyte ratio | 1.33 (1.07–1.65)* | 1.17 (0.95–1.46) | 1.85 (0.74–4.62) |
Platelet-to-lymphocyte ratio | 1.31 (1.07–1.60)* | 1.30 (1.06–1.60)* | 1.99 (0.82–4.81) |
Systemic immune-inflammation index | 1.19 (1.01–1.41)* | 1.15 (0.97–1.37) | 1.77 (0.87–3.63) |