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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: GPR34 in spinal microglia exacerbates neuropathic pain in mice

Fig. 4

Pro-inflammatory microglial molecules are reduced in GPR34-deficient mice. The ipsilateral L4 dorsal horn was obtained from WT and GPR34-deficient mice before (Naive) and after L4 nerve injury (n = 4 for each time point), and mRNA expression levels of neuropathic pain-related molecules were quantified by qRT-PCR. a TNF-α, b IL-1β, c IL-6, and d iNOS. Results are normalized to GAPDH. Data are shown as fold change over naive sample of WT mice. Values are mean ± SEM. **p < 0.01, ***p < 0.001 (two-way ANOVA with post-hoc Tukey’s test)

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