Fig. 2From: Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat modelBinding assay with patients’ sera on murine teased fibres using subclass-specific secondary antibodies. No binding to paranodes is visible after incubation with a control serum (a). The acute patient shows paranodal deposition of IgG3 and weakly of IgG4 (b). In the low titre and chronic patient, IgG4 can be identified as the binding subclass (c, d). Bar = 20 μmBack to article page