Table 5 General, demographic, and clinical findings of KIR haplotype, HLA allele, and their combination frequencies in subjects with acute ischemic stroke in relation to TOAST subtype
Variables | LAAS (n 45) | Lacunar (27) | Cardioembolic (40) | p |
|---|---|---|---|---|
Male (n/%) | 29 (64.4) | 12 (44.4) | 15 (37.5) | 0.057 |
Hypertension (n/%) | 39 (86.6) | 24 (88.8) | 36 (90) | 0.85 |
Diabetes (n/%) | 20 (44.4) | 13 (48.14) | 15 (37.5) | 0.40 |
Hypercholesterolaemia (n/%) | 24 (53.3) | 6 (22.22) | 10 (25) | 0.011 |
Hypertriglyceridaemia (n/%) | 12 (26.66) | 5 (18.51) | 9 (22.5) | 0.84 |
Atrial fibrillation (n/%) | 8 (17.77) | 8 (29.62) | 35 (87.5) | 0.0001 |
Previous stroke (n/%) | 21 (46.66) | 13 (48.14) | 21 (52.5) | 0.90 |
2DL1 (n/%) | 27 (60) | 13 (48.14) | 22 (55) | 0.75 |
2DL2 (n/%) | 20 (44.4) | 7 (25.92) | 12 (30) | 0.20 |
2DL3 (n/%) | 39 (86.6) | 17 (62.96) | 29 (72.5) | 0.033 |
2DL4 (n/%) | 40 (88.8) | 16 (59.25) | 26 (65) | 0.010 |
2DL5A (n/%) | 6 (13.33) | 1 (3.73) | 7 (17.5) | 0.37 |
2DL5B (n/%) | 13 (28.8) | 11 (40.7) | 14 (35) | 0.76 |
2DS1 (n/%) | 7 (15.5) | 7 (25.9) | 9 (22.5) | 0.52 |
2DS2 (n/%) | 14 (31.1) | 12 (44.4) | 17 (42.5) | 0.61 |
2DS3 (n/%) | 13 (28.8) | 6 (22.2) | 10 (25) | 0.92 |
2DS4 (n/%) | 20 (44.4) | 10 (37.03) | 16 (40) | 0.90 |
2DS5 (n/%) | 5 (11.11) | 4 (14.81) | 8 (20) | 0.73 |
3DL1 (n/%) | 34 (75.55) | 13 (48.14) | 28 (70) | 0.073 |
3DL2 (n/%) | 37 (82.22) | 14 (51.85) | 25 (62.5) | 0.016 |
3DL3 (n/%) | 36 (80) | 13 (48.14) | 22 (55) | 0.015 |
3DS1 (n/%) | 23 (51.1) | 14 (51.85) | 23 (57.5) | 0.35 |
2DP1 (n/%) | 39 (86.6) | 19 (70.37) | 30 (75) | 0.26 |
3DP1 (n/%) | 3 (6.66) | 4 (14.81) | 10 (25) | 0.11 |
HLA-A-Bw4 (n/%) | 8 (17.77) | 9 (33.3) | 12 (30) | 0.33 |
HLA-A haplotype (n/%) | 18 (40) | 12 (44.4) | 20 (50) | 0.68 |
HLA-C1 haplotype (n/%) | 13 (28.88) | 5 (18.51) | 19 (47.5) | 0.069 |
HLA-C2 haplotype (n/%) | 12 (26.66) | 9 (33.3) | 14 (35) | 0.83 |
HLA-B-Bw4-T (n/%) | 14 (31.11) | 4 (14.81) | 12 (30) | 0.37 |
HLA-B-Bw4 I (n/%) | 3 (6.66) | 1 (3.7) | 6 (15) | 0.42 |
2DL2-HLA-C1 (n/%) | 7 (15.5) | 4 (14.81) | 12 (30) | 0.24 |
2DL3-HLA-C1 (n/%) | 15 (33.3) | 8 (29.62) | 13 (32.5) | 0.67 |
2DS2-HLA-C1 (n/%) | 13 (28.87) | 11 (40.74) | 14 (35) | 0.54 |
2DS2-HLA-C2 (n/%) | 8 (17.77) | 9 (33.3) | 11 (27.5) | 0.40 |
2DL2-HLA-C2 (n/%) | 8 (17.77) | 7 (25.92) | 9 (22.5) | 0.24 |
2DS1-HLA-C2 (n/%) | 5 (11.11) | 2 (7.40) | 7 (17.5) | 0.67 |
2DL1-HLA-C1 (n/%) | 2 (4.4) | 4 (14.81) | 9 (22.5) | 0.047 |
2DL2-HLA-C1 (n/%) | 7 (15.5) | 4 (14.81) | 12 (30) | 0.24 |
2DL1-HLA-C2 (n/%) | 7 (15.5) | 3 (11.11) | 7 (17.5) | 0.88 |