Fig. 2

JC124 treatment reduced TBI-induced degenerative neurons. Representative images of ipsilateral cortex and dentate gyrus (DG) taken from FJB stained coronal sections from TBI-vehicle and TBI-JC124 animals. Quantification analysis showed in all three regions assessed including ipsilateral cortex, hilus, and DG granular cell layer, significantly less FJB+ cells were found in JC124-treated group as compared to the vehicle-treated group (p < 0.01, p < 0.05, and p < 0.01, respectively). Bar = 100 μm for cortex, bar = 400 μm for DG