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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury

Fig. 5

JC124 treatment diminished injury-enhanced focal and systemic expression of IL-1 beta. Expression level of IL-1 beta in the ipsilateral cortex (a) and peripheral blood (b) was measured with ELISA. In both the ipsilateral cortex (left) and serum samples (right), significantly increased expression of IL-1beta was only observed in the TBI-vehicle group (p < 0.01). TBI-JC124 group had similar expression level as sham

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Journal of Neuroinflammation

ISSN: 1742-2094