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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury

Fig. 6

JC124 treatment decreased post-injury expression of IL-1 beta. Representative western blotting image showing the 35 kDa band of IL-1 beta detected in the ipsilateral hippocampal lysate from sham, TBI-vehicle, and TBI-JC124 animals. The densitometry values in the bar graph showed that TBI vehicle group had significantly higher expression of IL-1 beta compared to sham and TBI-JC124 groups (p < 0.01 and p < 0.05, respectively). Compared to sham, IL-1 beta was slightly higher but not significant in TBI-JC124 group

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