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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury

Fig. 9

JC124 treatment decreased the expression level of iNOs following injury. Representative western blotting image showing the 130 kDa band of iNOs detected in the ipsilateral hippocampal lysate from sham, TBI-vehicle, and TBI-JC124 animals. The densitometry values in the bar graph showed that TBI induced significantly upregulation of iNOs when compared to sham (p < 0.0001), and JC124 treatment reduced the iNOs expression level in the injured animals (p < 0.05)

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Journal of Neuroinflammation

ISSN: 1742-2094