Fig. 5

Effects of baicalin on the PI3K/AKT/FoxO1 pathway in the hippocampus of CUMS-induced mice. a Western blot was performed to detect the protein levels of TLR4, p-PTEN, p-PI3K, p-AKT, and p-FoxO1 in the hippocampus (n = 4). b The levels of p-FoxO1 in cytoplasmic fractions and FoxO1 in the nuclear extractions were determined by western blot (n = 4). All data were normalized to the control group and presented as means ± SEM. ^#p < 0.05, ^##p < 0.01, ^###p < 0.005 vs. control; *p < 0.05, **p < 0.01 vs. CUMS