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Table 1 The stressors of CUMS protocol

From: Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway

Stressor

Duration

Water deprivation

12 h

Soiled cage

12 h

Food deprivation

12 h

Cage title (45°)

12 h

Empty bottle

12 h

Overnight illumination

12 h

Physical restrain

1 h

Cage shaking

10 min

Tail nipping

10 min

Overhang

10 min

Noise

10 min