Table 1 Descriptions of treatments tested including timing, dosage, and location
Groups | Treatments |
|---|---|
Control | T10 contusion, no treatment |
Systemic IL-10 | 50 μl IL-10 (concentration 5 μg IL-10/50 μl 1X PBS) via IP injection 30 min post-impaction |
Local IL-10 | 5 μl IL-10 (concentration 10 μg/1 ml 1X PBS) injected into the epicenter, 1 μL at a time in 30-s intervals |
MCMs | 5 μl MCMs (concentration 20 mg MCMs/1 ml 1X PBS) injected into the epicenter, 1 μL at a time in 30-s intervals |
MCMs+IL-10 | 5 μl MCMs bound with IL-10 (concentration 20 mg of IL-10 MCMs/1 ml 1X PBS) injected into the epicenter, 1 μL at a time in 30-s intervals |