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Table 1 Time to recovery analysis: CFA then drug

From: Morphine immunomodulation prolongs inflammatory and postoperative pain while the novel analgesic ZH853 accelerates recovery and protects against latent sensitization

  1. Comparison of each time point to the group baseline to determine when that group recovered (difference from baseline ns). Total time of significant hypersensitivity (days in pain) is noted in the right column. Morphine prolonged recovery compared to vehicle and ZH853 treatment. ZH853 expedited recovery versus vehicle and morphine treatment. “Day” indicates the number of days since CFA injection. Two-way ANOVAs for von Frey and Hargreaves were conducted separately. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001