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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Experimental necrotizing enterocolitis induces neuroinflammation in the neonatal brain

Fig. 2

Experimental NEC affects brain cell homeostasis. a Quantification of CC3 (Table 1) protein expression. Compared to breastfed control, NEC pups had higher levels of CC3 expression in the brain. b Immunohistochemistry images of CC3+ cells (left) and their quantification (right). Compared to breastfed control, NEC pups had increased density of CC3+ cells in the hippocampus, basal ganglia/thalamus, and the cerebral cortex. Scale bar = 100 μm. c Relative gene (left) and protein (right) expression of ER stress markers BiP and CHOP. NEC pups had higher gene and protein expression of ER stress markers. d Western blots of BiP, CHOP, CC3, and the loading control (β-actin)

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