Fig. 1

Expression of TREK-1 in the BBB of normal mice brain and perihematoma tissue after ICH. a The diagram of the experimental design in this study. b The localization of TREK-1 immunoreactivity was observed by immunofluorescent staining of TREK-1 (red) with GFAP (blue), and CD31 (green), respectively. Scale bar = 50 μm. c Representative western blot image of TREK-1 and GAPDH expression in perihematoma tissue. d Statistical analysis of western blots signals of TREK-1 in the perihematoma tissue of WT mice after ICH. The data were expressed as mean ± SEM and evaluated by one-way ANOVA with Tukey post hoc test (n = 5). *p < 0.05, sham group versus ICH 3d, 7d, and 14d groups