Fig. 2

TREK-1-deficient mice possess a larger hematoma volume on day 3 after ICH and more brain water content on day 7 post-ICH. a A representative MRI image on days 1 and 3 after ICH. b Representative image of HE staining on days 1 and 3 after ICH. c Statistic analysis of hematoma volume according to the HE staining. d Statistical analysis of brain water content using the wet/dry weigh method on days 1, 3, and 7 after ICH. e Representative western blot image of AQP4 expression in the perihematoma tissue. f Quantification of AQP4 expression according to the β-actin expression on days 1 and 3 after ICH. Values were expressed as mean ± SEM and data were evaluated by one-way ANOVA with Tukey post hoc test (n = 5–7). ^#p < 0.05, WT sham group versus KO ICH group, *p < 0.05, WT ICH group versus KO ICH group