From: NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes
References
Activation
High extracellular glucose
[33]
Hexokinase
[28, 37]
Extracellular ATP (eATP)
[34, 38]
β-amyloid
[39]
S. aureus
[35]
Cholesterol
[36]
Uric acid crystal
[40]
Alum
[41]
Low K+
[42]
Negative regulation
Autophagy
[43]
Nitric oxide
[44]
Type I IFNs
[45]
Measles virus (MV)
[46]
MiR-233
[47]
Effector and memory T cells
[48]