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Table 1 Literature regarding the regulation of the NLRP3 inflammasome

From: NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

  

References

Activation

High extracellular glucose

[33]

Hexokinase

[28, 37]

Extracellular ATP (eATP)

[34, 38]

β-amyloid

[39]

S. aureus

[35]

Cholesterol

[36]

Uric acid crystal

[40]

Alum

[41]

Low K+

[42]

Negative regulation

Autophagy

[43]

Nitric oxide

[44]

Type I IFNs

[45]

Measles virus (MV)

[46]

MiR-233

[47]

Effector and memory T cells

[48]