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Table 1 Clinical disease parameters of EAE

From: Contribution of LTi and TH17 cells to B cell aggregate formation in the central nervous system in a mouse model of multiple sclerosis

  EAE onset (days after immunization) Time point of experiment Final EAE score
Mice used for flow cytometry
 MP4-immunized mice at acute stage of disease  
  n = 2 × 5 14.40 ± 0.37 16.00 ± 0.33 2.55 ± 0.20
 MP4-immunized mice at chronic stage of disease  
  n = 1 × 5 and 1 × 6 18.18 ± 0.52 72.10 ± 0.31 2.48 ± 0.08
 MOG:35–55-immunized mice at acute stage of disease  
  n = 2 × 5 11.90 ± 0.59 13.50 ± 0.50 2.58 ± 0.20
 MOG:35–55-immunized mice at chronic stage of disease  
  n = 2 × 5 12.40 ± 0.79 54.00 ± 0.00 2.70 ± 0.06
Mice used for RNA sequencing
 MP4-immunized mice at chronic stage of disease  
  n = 9 21.00 ± 1.59 58.44 ± 1.76 2.22 ± 0.22
 MOG:35–55-immunized mice at acute stage of disease  
  n = 5 10.60 ± 0.40 13.00 ± 0.00 2.70 ± 0.05
  1. The mean of the values ± SEM is shown