Fig. 4From: The antidepressant effects of GM-CSF are mediated by the reduction of TLR4/NF-ĸB-induced IDO expressionSchematic representation of the mechanism underlying the antidepressant effects of GM-CSF. The figure illustrates an overview of the kynurenine pathway which is involved in LPS-induced depression. Our findings indicated that GM-CSF interferes with this pathway as shown in the figureBack to article page