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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Light-emitting diode therapy protects against ventricular arrhythmias by neuro-immune modulation in myocardial ischemia and reperfusion rat model

Fig. 6

Proposed hypothesis for the therapeutic effect of LED on VAs in myocardial I/R. Myocardial I/R might cause a series of changes directly or indirectly: microglia activation in the PVN and increase of LSG neural activity and inflammatory response in the myocardium. LED therapy might inhibit the microglia activation induced by myocardial I/R, thus suppressing the sympathetic activation and inflammatory response. These changes help to protect against VAs. I/R, ischemia-reperfusion; LED, light-emitting diodes; LSG, left stellate ganglion; NGF, nerve growth factor; PVN, paraventricular nucleus; VA, ventricular arrhythmia

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Journal of Neuroinflammation

ISSN: 1742-2094