| Brainstem | Cerebellum | |||||
---|---|---|---|---|---|---|---|
PID | PID | ||||||
7 | 14 | 21 | 7 | 14 | 21 | ||
TLR2/GADPH | Veh | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.4 | 1.0 ± 0.3 |
MOG/Veh | 0.7 ± 0.2 | 12.0 ± 2.8°°° | 4.6 ± 0.8 | 0.7 ± 0.0 | 17.3 ± 7.6°° | 16.2 ± 6.6° | |
MOG/PEALut | 1.0 ± 0.3 | 6.8 ± 1.9* | 3.2 ± 0.6 | 0.8 ± 0.4 | 2.6 ± 0.7* | 9.7 ± 4.8 | |
Fpr2/GADPH | Veh | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.4 | 1.0 ± 0.2 | 1.0 ± 0.1 |
MOG/Veh | 1.4 ± 0.5 | 45.6 ± 11.8°°° | 8.0 ± 2.8 | 1.3 ± 0.3 | 50.7 ± 26.2°° | 32.3 ± 13.0 | |
MOG/PEALut | 1.6 ± 0.5 | 24.6 ± 9.1* | 5.1 ± 1.4 | 1.9 ± 0.2 | 22.6 ± 11.2 | 17.3 ± 4.1 | |
CD3γ/GADPH | CTRL | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 |
MOG/Veh | 1.2 ± 0.6 | 72.7 ± 9.1°°° | 44.6 ± 11.4°°° | 1.5 ± 0.4 | 140.4 ± 72.2°° | 151.0 ± 40.7°° | |
MOG/PEALut | 1.3 ± 0.3 | 35.2 ± 14.4** | 31.8 ± 8.8 | 0.9 ± 0.3 | 31.0 ± 13.8* | 105.7 ± 33.9 | |
TCR-ζchain/GADPH | CTRL | 1.0 ± 0.3 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.4 | 1.0 ± 0.1 | 1.0 ± 0.1 |
MOG/Veh | 0.9 ± 0.2 | 45.1 ± 8.0°°° | 19.3 ± 4.6°° | 1.4 ± 0.3 | 10.6 ± 4.5°° | 8.5 ± 1.9° | |
MOG/PEALut | 0.8 ± 0.2 | 19.2 ± 7.5*** | 13.1 ± 3.3 | 1.4 ± 0.2 | 3.2 ± 1.1* | 7.1 ± 2.2 | |
CD137/GADPH | Veh | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 |
MOG/Veh | 1.0 ± 0.0 | 140.7 ± 47.0°°° | 11.9 ± 2.6 | 1.4 ± 0.0 | 27.9 ± 13.4°°° | 7.3 ± 1.4 | |
MOG/PEALut | 1.2 ± 0.0 | 50.9 ± 20.3** | 9.6 ± 2.2 | 1.8 ± 0.4 | 5.9 ± 1.2** | 6.0 ± 1.4 | |
CB2/GADPH | Veh | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.3 | 1.0 ± 0.0 | 1.0 ± 0.3 | 1.0 ± 0.2 |
MOG/Veh | 1.2 ± 0.1 | 19.0 ± 5.7°°° | 7.4 ± 2.0°° | 0.9 ± 0.1 | 8.1 ± 2.8°°° | 7.5 ± 1.9°° | |
MOG/PEALut | 1.5 ± 0.1 | 6.5 ± 2.5** | 6.3 ± 2.3 | 1.5 ± 0.3 | 2.9 ± 0.5* | 5.7 ± 1.8 | |
CB1/GADPH | Veh | 1.0 ± 0.2 | 1.0 ± 0.3 | 1.0 ± 0.2 | 1.0 ± 0.5 | 1.0 ± 0.2 | 1.0 ± 0.1 |
MOG/Veh | 0.8 ± 0.2 | 1.1 ± 0.3 | 1.2 ± 0.3 | 1.0 ± 0.2 | 0.9 ± 0.2 | 1.1 ± 0.1 | |
MOG/PEALut | 0.8 ± 0.1 | 1.3 ± 0.5 | 1.1 ± 0.3 | 1.6 ± 0.4 | 1.1 ± 0.3 | 0.9 ± 0.1 | |
MBP/GADPH | CTRL | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.0 | 1.0 ± 0.1 | 1.0 ± 0.1 |
MOG/Veh | 1.1 ± 0.0 | 0.9 ± 0.0 | 0.8 ± 0.0 | 0.8 ± 0.1 | 0.8 ± 0.2 | 1.1 ± 0.1 | |
MOG/PEALut | 1.1 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 01 | 1.0 ± 0.1 | 0.8 ± 0.1 | 0.9 ± 0.0 |