Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study

Table 2 Baseline OCT results of MOG-IgG-seropositive patients and HCs

Baseline results	HC	MOG-IgG-seropositive patients Eye^ON-	MOG-IgG-seropositive patients Eye^ON+	HC vs Eye^ON-			HC vs Eye^ON+			Eye^ON- vs Eye^ON+
	N (eyes) = 56	N (eyes) = 18	N (eyes) = 20	[B]	[SE]	[p]	[B]	[SE]	[p]	[B]	[SE]	[p]
GCIP [mean (SD)]	0.63 (0.04)	0.57 (0.07)	0.39 (0.12)	− 0.057	0.022	0.008	− 0.235	0.033	< 0.0001	− 0.178	0.037	< 0.0001
pRNFL [mean (SD)]	98.50 (9.17)	94.33 (15.92)	58.25 (22.56)	− 4.167	4.577	0.360	− 40.25	5.864	< 0.0001	− 36.08	6.311	< 0.0001
INL [mean (SD)]	0.27 (0.03)	0.26 (0.03)	0.30 (0.05)	− 0.014	0.009	0.110	0.026	0.013	0.046	0.041	0.014	0.004
MV [mean (SD)]	2.37 (0.10)	2.34 (0.11)	2.19 (0.13)	− 0.036	0.034	0.290	− 0.183	0.039	< 0.0001	− 0.147	0.042	0.0005
HCVA in logMAR [mean (SD)]	−0.09 (0.14)	0.05 (0.15)	0.55 (0.81)	0.146	0.059	0.013	0.394	0.134	0.0032	0.248	0.131	0.058

Abbreviations: B estimate, GCIP combined ganglion cell and inner plexiform layer, HC healthy control, INL inner nuclear layer, Eye^ON- MOG-IgG-seropositive patients without a history of ON, Eye^ON+ MOG-IgG-seropositive patients with a history of ON, OCT optical coherence tomography, ON optic neuritis, p p value, pRNFL peripapillary retinal nerve fiber layer, SD standard deviation, SE standard error, MV macular volume, vs versus, N number of eyes

ISSN: 1742-2094