Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study

Table 3 Longitudinal OCT results of MOG-IgG-seropositive patients and HCs

Longitudinal OCT data	HC	MOG-IgG-seropositive patients Eye^ON-	MOG-IgG-seropositive patients Eye^ON+	HC vs MOG-IgG-seropositive patients (Eye^ON- and Eye^ON+)				Eye^ON- vs Eye^ON+
Longitudinal OCT data	Absolute change to baseline			HC vs MOG-IgG-seropositive patients (Eye^ON- and Eye^ON+)				Eye^ON- vs Eye^ON+
	N (eyes) = 56	N (eyes) = 18	N (eyes) = 20	[B]	[95%CI]	[SE]	[p]	[B]	[95%CI]	[SE]	[p]
GCIP [mean (SD)]	0.00 (0.01)	0.00 (0.01)	0.00 (0.05)	− 0.000	− 0.004; 0.005	0.002	0.884	− 0.006	− 0.016; 0.003	0.005	0.214
pRNFL [mean (SD)]	− 0.61 (2.00)	− 4.5 (5.89)	− 1.60 (4.48)	− 1.645	− 2.819; − 0.471	0.599	0.009	0.168	− 1.380; 1.717	0.790	0.832
INL [mean (SD)]	0.00 (0.01)	0.01 (0.02)	0.00 (0.03)	0.002	−0.002; 0.005	0.002	0.312	− 0.003	− 0.011; 0.004	0.004	0.381
MV [mean (SD)]	0.00 (0.02)	− 0.01 (0.04)	− 0.01 (0.05)	− 0.008	− 0.016; 0.0013	0.004	0.103	0.002	− 0.013; 0.018	0.008	0.769

Abbreviations: 95%CI 95% confidence interval, B Estimate (beta-coefficient), GCIP combined ganglion cell and inner plexiform layer, HC healthy control, INL inner nuclear layer, Eye^ON- MOG-IgG-seropositive patients without a history of ON, Eye^ON+ MOG-IgG-seropositive patients with a history of ON, OCT optical coherence tomography, p p value, pRNFL peripapillary retinal nerve fiber layer, SD standard deviation, SE standard error, MV macular volume, vs versus, N number of eyes

ISSN: 1742-2094