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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

Fig. 2

Autophagy-related 5 (ATG5), Parkin, and lactate serum and cerebrospinal fluid (CSF) levels in 30 multiple sclerosis (MS) patients with magnetic resonance imaging (MRI) evidence of disease activity (Gd+) and 30 MS patients without MRI evidence of disease activity (Gd−). ATG5 serum and CSF levels were higher in Gd+ MS patients than in Gd− (unpaired t test; p < 0.0001) (a, b). Parkin serum and CSF concentrations were increased in Gd+ MS patients than in Gd− (Mann-Whitney; p < 0.0001) (c, d). Lactate serum levels were more elevated in Gd+ MS than in Gd− (Mann-Whitney; p < 0.0001) (e). Each point represents a single observation. Horizontal bars indicate means (a, b) or medians (ce)

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