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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity

Fig. 4

Characterization of DE genes in CD11b+CD45lo and CD11b+CD45hi cells of CD and WD-fed mice. a Principal component analysis (PCA) plot showing the first and second component of transcriptional expression profiles between CD11b+CD45lo and CD11b+CD45hi cells. b–d Box plots showing the gene expression in log2-transformed cpm in CD11b+CD45lo and CD11b+CD45hi cells from both CD and WD-fed mice. b Expression of marker genes of microglia, monocytes/macrophage, and granulocytes. c Expression of disease-associated microglia (DAM) genes. d Expression of complement cascade genes

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