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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation

Fig. 6

PDGFA expression is clinically relevant in glioma patients. a High-risk glioma correlated with the increased PDGFA expression, and the Kaplan-Meier survival curves of TCGA GBM patients indicated the correlation between low expressions of PDGFA in patients and the better overall survival significantly compared to patients with high PDGFA expressions. b Analyses of the Sun dataset (GSE4290) showing a higher expression of PDGFA in GBM than in NSC or non-tumor samples. c PDGFA gene expression value correlated with CEBPD expression in glioma samples from the Sun dataset (GSE4290). d Representative immunohistochemistry analyses of CEBPD and PDGFA in GBM and normal brain tissues. Scale bar, 50 μm. e PDGFA H-score value correlated with CEBPD H-score in glioma samples. (Data are expressed as mean ± SEM. Differences between groups were determined with the unpaired two-tailed t test for a and b. Pearson’s correlation (r) values are indicated for c and f)

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Journal of Neuroinflammation

ISSN: 1742-2094