Fig. 5
Myelin reactivity of splenocytes and lymph node cells obtained from tolDC- or PBS-treated EAE mice. MOG35–55-specific proliferation of splenocytes (a) and lymph node cells (b) at different time points during the in vivo EAE model. Cells were rechallenged with MOG35–55 or were left unstimulated as a negative control. The stimulation index was calculated as the mean counts per minute (cpm) of MOG35–55-stimulated conditions divided by the mean cpm of the non-stimulated conditions. The mean per treatment group is depicted as a vertical black line. pi post induction