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Table 2 Myelin-specific IFN-γ ELISPOT responses at different time points in the EAE disease course

From: Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA

  1. Number of responder mice is shown per myelin peptide, with between brackets the mean ratio of antigen-specific spot count over background spot count ± standard deviation. The following responder criteria were used: per 106 splenocytes, the mean antigen-specific spot count must be greater than or equal to 15 spots per well and at least 1.5 times as high as the background reactivity (i.e., the spot count in the negative control). pi post induction