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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis

Fig. 6

Mdivi-1 modulates systemic immune responses in EAE. Splenocytes of mice described in Fig. 1a were isolated on day 28 p.i., then directly analyzed with flow cytometry. a Mononuclear cells were gated and percentages of CD4+ T cells in that gate were quantitatively analyzed. b Percentage of Th1 cells in gated CD4+ T cells (CD4+ IFN-γ+), Th17 cells (CD4+ IL-17+), c Th2 cells (CD4+ IL-4+), Treg cells (CD4+IL-10+, CD4+Foxp3+). Data represent mean ± SEM (n = 5–8 each group). *P < 0.05. One representative of two experiments is shown

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