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Table 1 Mean ratio of [18F]DPA-714 binding (sonicated/non-sonicated) in the frontal cortex and hippocampus in all three groups of animals. The cerebellum was not sonicated and is used as control

From: In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study

Region of interestMean ratio of ipsilateral/contralateral
1 sonication
N = 6
2 sonications
N = 8
6 sonications
N = 5
Frontal cortex1.47 ± 0.21.53 ± 0.21.53 ± 0.3
Hippocampus1.31 ± 0 .11.83 ± 0.51.61 ± 0.5
Cerebellum1.03 ± 0.041.02 ± 0.070.98 ± 0.12