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Table 2 Mean ratio of [18F]DPA-714 binding (sonicated/non-sonicated) in the frontal cortex and hippocampus in animals that were followed longitudinally after two and six sonications. The cerebellum was not sonicated and is used as control

From: In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study

Region of interestMean ratio of ipsilateral/contralateral
2 sonications6 sonications
Frontal cortex1.74 ± 0.11.64 ± 0.3
Hippocampus2.31 ± 0.71.74 ± 0.6
Cerebellum1.10 ± 0.041.02 ± 0.1