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Table 2 Mean ratio of [18F]DPA-714 binding (sonicated/non-sonicated) in the frontal cortex and hippocampus in animals that were followed longitudinally after two and six sonications. The cerebellum was not sonicated and is used as control

From: In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study

Region of interest

Mean ratio of ipsilateral/contralateral

2 sonications

6 sonications

Frontal cortex

1.74 ± 0.1

1.64 ± 0.3

Hippocampus

2.31 ± 0.7

1.74 ± 0.6

Cerebellum

1.10 ± 0.04

1.02 ± 0.1