Fig. 6
From: The retinal environment induces microglia-like properties in recruited myeloid cells
Recruitment of donor CD45+CD11b+ cells into the retina in radiation bone marrow chimeras. Chimeric mice received 2 × 6 Gy of radiation and were unshielded. a Flow cytometry analysis of chimerism in retinas of mice grafted with B6-CD45.1+ bone marrow into irradiated B6-CD45.2+ recipients assayed at the indicated time points. Overall number retinal CD45+ cells and the number of the host and donor cells is indicated. Cell numbers are given as mean ± SD. Gray shaded area indicates mean ± 1 SD of the total number of mononuclear cells in retina prior to radiation and bone marrow grafting. b Analysis of chimerism in the brain from the same mice as a. c Incorporation of donor bone marrow-derived cells expressed as percent donor chimerism. Cells were gated on CD45medCD11b+ cells