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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion

Fig. 4

Mo-derived perivascular Mφs inhibit endothelial cell apoptosis. Representative images of the inner aspect of the of ColIV (red) and TUNEL (green) double staining of the occluded vein area 3 days after the occlusion in control liposome (a) and clodronate liposome (b)-treated mice. Quantification of ColIV+TUNEL+ cells on the occluded area and comparison between control liposome and clodronate liposome-injected mice (c, n = 8, Mann-Whitney t test, *P = 0.0004) and between WT and Ccr2GFP/GFP mice (d). lipo, control liposome-treated; lipo-clo, liposome clodronate-treated; ColIV, collagen IV; TUNEL, terminal deoxynucleotidyl tranferase dUTP nick end labeling. Scale bar a and b = 10 μm

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