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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis

Fig. 3

Astrocyte-restricted ablation of RelB delays the onset of EAE. EAE was induced in WT (RelBloxP/loxP) and RelBΔAST mice. a, b Clinical scores were recorded for 24 days. n = 15–16 mice per group. a Multiple T tests (*p < 0.05). b T tests: day of onset (F = 4.274, p = 0.013); day of peak (F = 2.129, p = 0.184); peak score (F = 1.390, p = 0.554). c At the peak of disease, lumbar spinal cords (L2–L4) (left panels) were stained with hematoxylin and eosin. Quantification of immune cells infiltration into peripheral regions of spinal cords. n = 6, T test: F = 4.879, t test p = 0.824

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