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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese

Fig. 2

Multiple sclerosis risk-associated amino acid positions of the HLA genes. Diamonds represent the –log10(P) of the amino acid positions of the tested HLA genes. Labeled red diamonds represent the –log10(P) values of the amino acid positions significantly associated with MS. The horizontal lines represent the association P value of HLA-DRB1*15:01. a No amino acid polymorphisms of HLA-B was significantly associated with MS. b No amino acid polymorphisms of HLA-DRB1 is significantly associated with MS. c The HLA-DQβ1 position 9 and 70 were associated with MS more significantly than HLA-DRB1*15:01

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Journal of Neuroinflammation

ISSN: 1742-2094