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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Viral-mediated gene delivery of TMBIM6 protects the neonatal brain via disruption of NPR-CYP complex coupled with upregulation of Nrf-2 post-HI

Fig. 3

Silencing BI-1 or Nrf-2 increased percent infarcted area at 72 h Post-HI. Quantitative analysis of percent infarcted area after administration of BI-1 or Nrf-2 siRNA (a, b) (data expressed as mean ± SD; an asterisk indicates p < 0.05 vs sham; number sign p < 0.05 vs vehicle; @ p < 0.05 vs Ad-TMBIM6 or scramble; n = 6–8/group using one-way ANOVA followed by Tukey’s multiple-comparison post hoc analysis)

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