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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Viral-mediated gene delivery of TMBIM6 protects the neonatal brain via disruption of NPR-CYP complex coupled with upregulation of Nrf-2 post-HI

Fig. 7

Fluorescent staining demonstrated BI-1’s ability to reduce ROS and attenuate inflammation at 72 h post-HI. DHE staining for ROS positive cells in the cortex (a). DHE staining around ventricles for ROS positive cells (b). Immunofluorescence and MPO-positive cell counting in peri-infarcted region (c). Red was for ROS or MPO staining and blue was for DAPI. Merge showed the number of positively stained cells (ac) (for panel a, scale bar = 50 μm; for panel b, scale bar = 100 μm; for panel c, scale bar = 25 μm; n = 3/group)

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