Fig. 8

BI-1 exerts its anti-inflammatory effects via inhibition of P4502E1 in an in vitro OGD model. Representative picture of western blot bands (a). Quantification analysis of BI-1, IL-6, TNFα, IL-1β, P4502E1, pNrf-2 (b–g) and percent cell viability (h). Data represent ± SD; an asterisk indicates p < 0.05 vs control; number sign p < 0.05 vs vehicle; @ p < 0.05 vs Ad-TMBIM6 and scramble; dollar sign p < 0.05 vs BI-1 siRNA; n = 4–5/group using one-way ANOVA followed by Tukey’s multiple-comparison post hoc analysis