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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Nrf-2 signaling inhibits intracranial aneurysm formation and progression by modulating vascular smooth muscle cell phenotype and function

Fig. 1

The effect of Nrf-2 activation on IA formation and progression. a Rate of aneurysm formation and rupture in the control and tBHQ treatment groups. (a) normal vessels, (b) aneurysmal artery (AA), (c) aneurysm (IA), (d) multiple aneurysms (MIA), (e) ruptured aneurysm (MIA), (f) quantitative analysis of (a) through (e) in the control and tBHQ treatment groups (N = intracranial aneurysms amounts under different condition). b (a) HE staining of normal cerebral artery (bar = 50 μM), (b) HE staining of IA (scale bar = 50 μM), (c) aneurysmal scores of the control and tBHQ treatment groups. Aneurysmal scores in the control group were much higher than that in the tBHQ group. (a) through (e). A corresponding to aneurysmal score of 1 to 5.*p < 0.05 compared with the control group

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