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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Nrf-2 signaling inhibits intracranial aneurysm formation and progression by modulating vascular smooth muscle cell phenotype and function

Fig. 3

a Cell viability assays. (a) Viability changes of VSMCs treated with different concentrations of H2O2. Data are the means ± standard errors of the mean. *p < 0.05 compared with the control group. (b) Viability changes of VSMCs treated with different concentrations of tBHQ. Data are the means ± standard errors of the mean. *p < 0.05 compared with the control group. b Intracellular ROS in the control and H2O2 groups. Data are the means ± standard errors of the mean. *p < 0.05 compared with the control group. c Effect of Nrf-2 activator and inhibitor on H2O2 induced intracellular ROS levels. (a) control, (b) H2O2, (c) tBHQ, (d) ML 385. Data are the means ± standard errors of the mean. DCFH-DA lobe was used to measure levels of intracellular levels of ROS. *p < 0.05 compared with the control group; #p < 0.05 compared with the H2O2 group

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Journal of Neuroinflammation

ISSN: 1742-2094