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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Preactivation of Notch1 in remote ischemic preconditioning reduces cerebral ischemia-reperfusion injury through crosstalk with the NF-κB pathway

Fig. 7

RIPC significantly reduced hippocampal neuronal cell apoptosis in rats after MCAO/R. However, the neuroprotective effects were attenuated by an inhibitor of the Notch1 signaling pathway. a Apoptosis was assayed by TUNEL, NeuN, and DAPI immunofluorescence staining. b The percent of TUNEL and NeuN double-positive cells. **P < 0.01 vs. the Sham group, #P < 0.05 vs. the MCAO/R group, &P < 0.05 vs. the RIPC + MCAO/R + DMSO group

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