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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Effect of Enterococcus faecalis 2001 on colitis and depressive-like behavior in dextran sulfate sodium-treated mice: involvement of the brain–gut axis

Fig. 10

Altered levels of XIAP and cleaved caspase-3 in the hippocampus after Enterococcus faecalis 2001 (EF-2001) administration. a Representative immunoblots probed with antibodies against hippocampal XIAP, cleaved caspase-3, and β-actin, as indicated. b, c Quantification of normalized values of XIAP and cleaved caspase-3 levels with β-actin in the hippocampus. XIAP is expressed in microglia in the hippocampus of dextran sulfate sodium (DSS)-treated mice treated with EF-2001. Microscopy images of XIAP (red), DAPI (blue), and GFAP or Iba1 (green) immunostaining in the dentate gyrus region of the hippocampus (d). The boxed area is shown in higher magnification. Bars represent means ± standard error of mean (SEM). **p < 0.01 vs. vehicle-treated water group. #p < 0.05 and ##p < 0.01 vs. vehicle-treated DSS group (n = 4–6 per group)

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