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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis

Fig. 3

a Optic nerves of mice 120 days after MOG or MBP immunization stained by H&E and CD3, Iba1, or MBP antibodies. Optic nerves were compared by an established infiltration score according to H&E staining (b) (Shindler et al. [3]), MBP score for the myelin status (c), Iba1 fluorescence intensity measurement for microglia activation (d), and CD3+ cell infiltration (e). The bar graphs represent the pooled mean ± standard deviation of at least two separate EAE experiments each with at least four animals per group; one optic nerve per mouse was included, *P < 0.05; **P < 0.01; ***P < 0.001; n.s., not significant, by ANOVA with Dunnett’s post hoc test compared to sham-treated mice

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