Fig. 4
From: Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain
Effects of intrathecal injection of microglial inhibitor and astroglial toxin on carrageenan-induced early- and late-phase mechanical allodynia in prostatitis mice. a, b Prostatitis-induced mechanical hypersensitivity in the lower abdominal area at 2 weeks was partially reversed by spinal injection of minocycline (50 μg) and L-AA (50 nmol). c, d Prostatitis-induced mechanical hypersensitivity in the lower abdominal area at 5 weeks was not reversed by spinal injection of minocycline (50 μg), but partially reversed and L-AA (50 nmol). BL, baseline. *P < 0.05, vs. Carr 2w or Carr 5w, two-way ANOVA, followed by post hoc Bonferroni test. n = 6 mice/group. All data are expressed as mean ± S.E.M. Arrows indicate drug injection