Fig. 5
From: Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain
Prostatitis induced ERK activation in spinal cord dorsal horn and contributed to mechanical allodynia. a Western blotting shows that prostatitis induced pERK expression in SDH 4 weeks after carrageenan injection into the prostate. Right, quantification of pERK levels in SDH in the carrageenan-treated group and the saline-treated group. *P < 0.05, vs. control (con, saline-treated group), Student’s t test. n = 4 mice/group. b Inhibition of prostatitis-induced mechanical allodynia in the lower abdominal area by intrathecal injection of U0126 (10 μg) at 5 weeks. BL, baseline. *P < 0.05, vs. Carr 5w, two-way ANOVA, followed by post hoc Bonferroni test. n = 6 mice/group. All data are expressed as mean ± S.E.M. Arrows indicate drug injection