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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Exosomes derived from statin-modified bone marrow dendritic cells increase thymus-derived natural regulatory T cells in experimental autoimmune myasthenia gravis

Fig. 5

Exosomes increased the expression of CD40 in the thymus. There is no change in the expression of CD40 on cTEC among the three experimental groups (a). Both DMSO and statin-treated DC-derived exosomes had significantly increased CD40 expressions on mTEC (b) and tDCs (c) compared with the PBS treated control group (*p < 0.05 and **p < 0.01). Data were presented as mean ± SEM from two independent experiments (n = 5 in the control group; n = 6 in DMSO-Dex and statin-Dex groups). The significance of the differences was evaluated by ANOVA, followed by Bonferroni test as a post hoc test

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