MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Table 1 The table of postmortem human samples used in this study

Gender	Age of onset	Age of death	Clinical diagnosis and pathological assessment	TDP + NCIs	TDP + GCIs	TDP + DNs	PMI/h
M	59	61	sALS with TDP-43	+	0	0	29
M	53	61	sALS with TDP-43	+	0	0	13
M	71	73	sALS with TDP-43	0	+	0	23
M	61	64	sALS with TDP-43	0	+	0	14
M	59	64	sALS with TDP-43	+	++	+	19
M	37	40	sALS with TDP-43	+	++	+	19
M	55	57	fALS with TDP-43	+	+++	0	18
F	78	82	fALS with TDP-43	++	0	0	36
F	62	64	sALS with TDP-43	+	+	0	19
F	NA	55	ALS FTLD TDP type B	+	++	0	5
F	NA	70	ALS FTLD TDP type B	+	+++	+	11
M	NA	62	ALS FTLD TDP type B	Rare	+	Rare	12
M	N/A	54	Normal control	0	0	0	12
M	N/A	72	Normal control	0	0	0	14
F	N/A	78	Normal control	0	0	0	8

Information about age, sex, clinical diagnosis, and the type of TDP-43 pathology is included. NCIs neuronal cytoplasmic inclusions, GCIs glial/microglial cytoplasmic inclusions, DNs extracellular dystrophic neuritis, PMI/h postmortem interval in hours

ISSN: 1742-2094