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Table 1 Demographic data of the study cohort

From: Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

  Gd−
(n = 20)
Gd+
(n = 26)
p value
Age (mean ± SD) 31.15 ± 10.37 36.15 ± 8.65 0.081
Sex (male/female)    0.818
 Male 6 (30.00%) 7 (26.92%)  
 Female 14 (70.00%) 19 (73.08%)  
 EDSS at sampling (median, Q1–Q2) 2 (1–2.5) 2 (1.5–2.13) 0.819
OCGB (N/P)    0.432
 Negative 1 (5.26%) 0 (0.00%)  
 Positive 18 (94.74%) 25 (100.00%)  
LS_OCMB (N/P)    0.393
 Negative 14 (73.68%) 16 (61.54%)  
 Positive 5 (26.32%) 10 (38.46%)  
T2 lesions    0.004
  < 9 lesions 12 (66.67%) 4 (16.67%)  
 10–20 lesions 5 (27.78%) 10 (41.67%)  
 21–50 lesions 1 (5.56%) 8 (33.33%)  
 51–100 lesions 0 (0.00%) 2 (8.33%)  
  1. Gd− patients without gadolinium-enhanced lesions, Gd+ patients with gadolinium-enhanced lesions; SD standard deviation, OCBG oligoclonal IgG bands; N/P negative/positive, LS_OCMB lipid-specific oligoclonal IgM bands