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Table 1 Demographic data of the study cohort

From: Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

 Gd−
(n = 20)
Gd+
(n = 26)
p value
Age (mean ± SD)31.15 ± 10.3736.15 ± 8.650.081
Sex (male/female)  0.818
 Male6 (30.00%)7 (26.92%) 
 Female14 (70.00%)19 (73.08%) 
 EDSS at sampling (median, Q1–Q2)2 (1–2.5)2 (1.5–2.13)0.819
OCGB (N/P)  0.432
 Negative1 (5.26%)0 (0.00%) 
 Positive18 (94.74%)25 (100.00%) 
LS_OCMB (N/P)  0.393
 Negative14 (73.68%)16 (61.54%) 
 Positive5 (26.32%)10 (38.46%) 
T2 lesions  0.004
  < 9 lesions12 (66.67%)4 (16.67%) 
 10–20 lesions5 (27.78%)10 (41.67%) 
 21–50 lesions1 (5.56%)8 (33.33%) 
 51–100 lesions0 (0.00%)2 (8.33%) 
  1. Gd− patients without gadolinium-enhanced lesions, Gd+ patients with gadolinium-enhanced lesions; SD standard deviation, OCBG oligoclonal IgG bands; N/P negative/positive, LS_OCMB lipid-specific oligoclonal IgM bands