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Table 1 Demographic data of the study cohort

From: Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

 

Gd−

(n = 20)

Gd+

(n = 26)

p value

Age (mean ± SD)

31.15 ± 10.37

36.15 ± 8.65

0.081

Sex (male/female)

  

0.818

 Male

6 (30.00%)

7 (26.92%)

 

 Female

14 (70.00%)

19 (73.08%)

 

 EDSS at sampling (median, Q1–Q2)

2 (1–2.5)

2 (1.5–2.13)

0.819

OCGB (N/P)

  

0.432

 Negative

1 (5.26%)

0 (0.00%)

 

 Positive

18 (94.74%)

25 (100.00%)

 

LS_OCMB (N/P)

  

0.393

 Negative

14 (73.68%)

16 (61.54%)

 

 Positive

5 (26.32%)

10 (38.46%)

 

T2 lesions

  

0.004

  < 9 lesions

12 (66.67%)

4 (16.67%)

 

 10–20 lesions

5 (27.78%)

10 (41.67%)

 

 21–50 lesions

1 (5.56%)

8 (33.33%)

 

 51–100 lesions

0 (0.00%)

2 (8.33%)

 
  1. Gd− patients without gadolinium-enhanced lesions, Gd+ patients with gadolinium-enhanced lesions; SD standard deviation, OCBG oligoclonal IgG bands; N/P negative/positive, LS_OCMB lipid-specific oligoclonal IgM bands