Fig. 1

Hypoxia-ischemia induces tissue loss and delay of neurological reflexes. a Average weights ± S.E.M. of hypoxic and sham rats starting from P7 (1-day prior the intervention) (HI male (n = 13), sham male (n = 8), HI female (n = 6), sham female (n = 7)). b Representative images of brain lesion induced by acute (24 and 72 h) and chronic hypoxia-ischemia (4 weeks). c Average day ± S.E.M. of the appearance of physical and neurological reflexes in sham and HI rats. HI mice (n = 19), sham mice (n = 15). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. control rats