Fig. 7

AG490 treatment inhibited astrogenesis at 28 days in SVZ ipsilateral side of GET-1 and Ntg mice after tMCAO. Images show representative immunostaining profile for BrdU+GFAP+ cells in ipsilateral SVZ of Ntg (a-control Vs b AG490 treated) and GET-1 (c-control Vs d AG490 treated) mice 28 days after tMCAO. (positive signals indicated by white arrows, red = GFAP, green = BrdU). Scale bar = 100 μm. e Bar graphs depicting the number of BrdU/GFAP co-labeled cells in ipsilateral SVZ of Ntg and GET-1 mice after AG490 and vehicle treatment 28 days after tMCAO. ** p < 0.05 V.Ntg+Vehicle group, ## p < 0.01 ### p < 0.001V.GET-1+Vehicle group